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Sexual behavior of the male partner may be as or more important than a woman's personal sexual behavior in predicting the women's risk of HPV infection and cervical disease. Little is known about the natural history of human papillomavirus (HPV) infection in men largely because of inadequate sample collection for HPV DNA testing and the inconsistencies in where the appropriate site is to sample. This study uses a sensitive method for collecting genital HPV samples developed by the PI to: (1) determine the proportion of men infected with any type of oncogenic HPV variant; (2) characterize behaviors that put men at risk for HPV infection; and (3) describe HPV infection in men as measured by duration and HPV DNA levels, antibodies for specific types of HPV, duration of these antibodies, and the development of genital warts. The long-term goal of this study is to develop cost-effective approaches for preventing HPV-related cancers in men and their partners.
For more information contact NCI Program Director: Vaurice Starks
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