Knowledge Synthesis of Genes and Cancer
What is Knowledge Synthesis?
An evidence-based synthesis that takes into account the amount of evidence, the extent of replication and protection from bias from meta-analyses and systematic reviews in any given subject.
A group met in Venice, Italy, on November 9–10, 2006 and developed the Venice Criteria as guidelines on how to assess cumulative epidemiologic evidence in genetic associations.
Genetic Associations in Cancer-Building a Knowledge Synthesis
Cancer Genetics Meta-Analyses and HuGE Reviews
This link takes you to all Meta-Analyses and HuGE Reviews of genetic associations in Human Cancer Epidemiology.
Cancer Related Genome Wide Association Studies
This link takes you to all publications of Genome Wide Associations in Cancer.
Genomic Applications in Cancer Care and Prevention
The January 2009 issue of Genetics in Medicine’s issue is dedicated to evidence based reviews and recommendations related to the use of genomic applications in practice from the EGAPP working group. The issue includes commentary, methods of the working group and three cancer-related topics reviews and recommendations.
Challenges and opportunities for evidence-based genetics practice. A commentary by Reed V. Tuckston MD, FACP
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) initiative: methods of the EGAPP Working Group. An article from the EGAPP Working Group
EGAPP Recommendation Statements
Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives.
STrengthening the REporting of Genetic Association Studies (STREGA)
The Human Genome Epidemiology Network (HuGENet) has recently released recommendations for STrengthening the REporting of Genetic Association Studies (STREGA). This initiative builds on the STrengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement and provides additions that are important to consider in genetic association studies to 12 of the 22 items on the STROBE checklist.