Resource Guide for Cancer Control and Population Sciences Applicants to the NCI Provocative Questions (PQ) FOA: Provocative Question Research Priorities in Cancer Control and Population Sciences
| PQ# | Provocative Question | Question Specific Resources |
|---|---|---|
| PQ – 1 | How does obesity contribute to cancer risk? | DCCPS Energy Balance Research |
| PQ – 2 | What environmental factors change the risk of various cancers when people move from one geographic region to another? | Geographic Information Systems at NCI Cohort Consortium |
| PQ – 3 | Are there ways to objectively ascertain exposure to cancer risk using modern measurement technologies? | Biospecimen Resources for Cancer Epidemiologists Cohort Consortium |
| PQ – 4 | Why don't more people alter behaviors known to increase the risk of cancers? | DCCPS Behavioral Research Program |
| PQ – 5 | Given the evidence that some drugs commonly and chronically used for other indications, such as an anti-inflammatory drug, can protect against cancer incidence and mortality, can we determine the mechanism by which any of these drugs work? | Pharmacoepidemiology and Pharmacogenomics Databases Biospecimen Resources for Cancer Epidemiologists Cohort Consortium |
| PQ – 6 | What are the molecular and cellular mechanisms by which patients with certain chronic diseases have increased or decreased risks for developing cancer, and can these connections be exploited to develop novel preventive or therapeutic strategies? | Biospecimen Resources for Cancer Epidemiologists Cohort Consortium |
| Are there definable properties of a non-malignant lesion that predict the likelihood of progression to invasive or metastatic disease? | Breast Cancer Surveillance Consortium | |
| Why do second, independent cancers occur at higher rates in patients who have survived a primary cancer than in a cancer-naïve population? | DCCPS Cancer Survivorship Research New Malignancies Among Cancer Survivors: SEER Cancer Registries, 1973-2000 Cohort Consortium IOM Report: From Cancer Patient to Cancer Survivor: Lost in Translation |
For a complete list of Provocative Questions, visit the NCI Provocative Questions website: http://provocativequestions.nci.nih.gov/
