Cognitive Effects of Cancer and Cancer Treatment
Cognitive dysfunction has been demonstrated in cancer patients before, during, and following treatment. It is believed that one-third of patients undergoing chemotherapy experience some degree of cognitive dysfunction during or following treatment, and these deficits can have a significant impact on social and occupational functioning, and overall quality of life. These cognitive difficulties may involve multiple cognitive domains, including working memory, executive function, and processing speed.
- Understand the mechanisms that underlie cognitive dysfunction associated with cancer and its treatment (e.g., surgery, chemotherapy, radiotherapy, hormone therapy)
- Identify risk factors for cognitive dysfunction associated with cancer and its treatment
- Examine the structural and functional changes in the brain associated with cognitive dysfunction
- Develop new methods to assess the typically subtle cognitive changes experienced by cancer patients in everyday life
- Distinguish the cognitive changes experienced by cancer patients from those of normal aging and pre-dementia