In Utero Exposure

Late effects on neurobehavioral and developmental trajectories and innovative neuropsychological assessments.


While there is an increasing body of science examining the prognosis and treatment of cancer patients and survivors during pregnancy, a significant gap in literature exists in the neurodevelopmental outcomes of in utero exposure. Much of the literature has focused on short-term follow-up and neonate malformations. Longer-term follow-up of the children who were exposed in utero to their mother's cancer treatment are needed.

Specific Aims

  • Foster expertise and further research in this area, particularly on neurodevelopmental cognitive outcomes
  • Develop new and leverage current clinical and epidemiological databases that link mother/child data to track outcomes over longer periods of times, particularly into pre-school and primary grades
  • Provide accurate data and research to inform clinical practice

Biobehavioral and Psychological Sciences at NCI: Building Bridges to Maximize Functioning
Dr. Lynne Padgett discusses research in cognitive effects of cancer treatment and psychosocial distress in the context of cancer control.


Paige Green, Ph.D., M.P.H.

Back to Key Initiative: Cognitive Changes Related to Cancer and Cancer Treatments