Supplemental Interest Project 16-005: Multilevel Communication Strategies to Promote HPV Vaccination Uptake


In partnership with the Centers for Diseases Control and Prevention (CDC), NCI is funding a Prevention Research Program Special Interest Project (SIP) focused on the development of multilevel health communication strategies to promote HPV vaccination in underserved or high-risk populations. 

This Supplemental Interest Project, titled Multilevel Communication Strategies to Promote HPV Vaccination Uptake, was established by the NCI and CDC in response to the 2012-13 President’s Cancer Panel Report, “Accelerating HPV Vaccine Uptake: Urgency for Action to Prevent Cancer,” which emphasized the need to develop, test, and collaborate with partner organizations to deploy integrated comprehensive communication strategies for relevant target populations in order to increase HPV vaccination rates in the U.S.

The overall goal of the SIP is to promote the development and testing of multilevel communication strategies that will enhance parent/caregiver or provider vaccine acceptability, increase knowledge of vaccine benefits, address common misperceptions about the HPV vaccine, address both initiation and completion of the vaccine series, reduce concerns about vaccine safety, and increase knowledge of cancer risk due to HPV as well as knowledge about HPV prevention.

Funded studies under the SIP are expected to develop and test HPV communication messages for underserved or high-risk populations that are sensitive to cultural, literacy/health literacy, and language differences; access issues; and medical mistrust among the target population. The projects must also develop and test multilevel communication strategies that target at least two levels within an ecologic framework and collaborate with key community partners. These multilevel communication strategies should seek to enhance the acceptability of HPV vaccination, increase behavioral intentions to vaccinate among parents with vaccine-eligible children, and/or increase behavioral intentions among providers to recommend HPV vaccination.

The following three centers have received awards under Supplemental Interest Project 16-005:

  • Healthy Youth Development Prevention Research Center, University of Minnesota (PI: Hee Yun Lee)
  • Health Promotion and Disease Prevention Research Center, University of Washington (PI: Rachel L. Winer)
  • Center for Health Promotion and Disease Prevention, University of North Carolina-Chapel Hill (PI: Noel T. Brewer)


April Oh, Ph.D., MPH
Program Director