Intervention Research to Improve Native American Health (IRINAH)

Intervention Research to Improve Native American Health (IRINAH), a network of principal investigators and their partners, funded by the National Institutes of Health (NIH), was launched in 2011 through a program titled “Interventions for Health Promotion and Disease Prevention in Native American (NA) Populations.”

Native American populations are exposed to considerable risk factors that significantly increase their likelihood of chronic disease, substance abuse, mental illness, oral disease, and HIV infection. The IRINAH program was created to develop, adapt, and test the effectiveness of health-promotion and disease-prevention interventions in NA populations. The long-term goal of the notice of funding opportunity (NOFO) is to reduce mortality and morbidity in NA communities. IRINAH also provides a forum for discussions on the challenges and opportunities to improve health in NA populations across the United States.

The first funding opportunity was through PAR-11-346, followed by the second round of funding in 2014 (PAR-14-260), and a reissuance in 2017 for both R01 (PAR-17-464) and R21 (PAR-17-496) applications and again in 2020 for both R01 (PAR-20-238) and R21 (PAR-20-214). The most recent reissuance was in 2023 for both R01 (PAR-23-298) and R21 (PAR-23-299), which also included a funding opportunity for R34 (PAR-23-285) applications, with the following due dates: October 21, 2024; October 21, 2025; and October 21, 2026.

A webinar on the IRINAH Program was held on January 25, 2024 to discuss the new NOFOs—R01 PAR-23-298, R21 PAR-23-299, and R34 PAR-23-285.The webinar materials, including slides, recording, and a list of FAQs are available here: https://go.nih.gov/nKOyz6b.

Questions? 

Contact Dr. Alexa Romberg at alexa.romberg@nih.gov, Dr. Sarah Vidal at sarah.vidal@nih.gov, or Dr. Kylee Probert at kylee.probert@nih.gov.