Implementation Science Centers in Cancer Control (ISC3)

Implementation Science Centers in Cancer Control (ISC3)

The Implementation Science Centers in Cancer Control (ISC3) Program supports the rapid development, testing, and refinement of innovative approaches to implement a range of evidence-based cancer control interventions. Centers all feature "implementation laboratories" involving clinical and community sites that will engage in implementation research across the cancer control continuum to advance methods in studying implementation and develop and validate reliable measures of key implementation science constructs. These Centers collectively provide leadership for an Implementation Science consortium across this and other Cancer MoonshotSM initiatives.

Implementation Science Centers (P50s)

The ISC3 Program is composed of six Centers funded by RFA-19-005 and RFA-19-006. To explore funded sites, click on the icon in the top left corner of the map, click on any pin on the map, or scroll down to view a funded initiatives table.

Center PI/MPI Institution Grant #
The Implementation Science Center for Cancer Control Equity

Karen Emmons
Elsie Taveras

Harvard T.H. Chan School of Public Health 1 P50 CA244433-01
Building Research in Implementation and Dissemination to close Gaps and achieve Equity in Cancer Control (BRIDGE-C2) Center Jennifer DeVoe Oregon Health & Science University 1 P50 CA244289-01
Colorado ISC3

Russell E. Glasgow

University of Colorado School of Medicine 1 P50 CA244688-01
Optimizing Implementation in Cancer Control: OPTICC

Bryan J. Weiner
Margaret Hannon
Cara C. Lewis

University of Washington 1 P50 CA244432-01
iDAPT: Implementation and Informatics - Developing Adaptable Processes and Technologies for Cancer Control

Kristie Long Foley
Thomas Houston

Wake Forest School of Medicine 1 P50 CA244693-01
Washington University Implementation
Science Center for Cancer Control (WU-ISCCC)

Ross C. Brownson
Graham A. Colditz

Washington University in St. Louis 1 P50 CA244431-01

Overview of Implementation Science Themes

Research activities for the Centers are organized around a cohesive, overarching implementation science theme that frames their activities and research agenda.

Harvard T.H. Chan School of Public Health: The Implementation Science Center for Cancer Control Equity at Harvard is improving community health by integrating health equity and implementation science for evidence-based cancer control.

Oregon Health & Science University: The BRIDGE-C2 Center will focus on advancing implementation science to improve cancer screening and prevention in underserved populations.

University of Colorado School of Medicine: University of Colorado Denver will focus on pragmatic approaches to assess and enhance the value of cancer prevention and control in rural primary care.

University of Washington: The OPTICC Center will develop, test, and refine innovative methods for optimizing the implementation of evidence-based interventions in cancer control.

Wake Forest School of Medicine: iDAPT will advance the field of implementation science by using technologies to support rapid cycle and real-time deployment and testing of implementation processes and adaptations within cancer control.

Washington University in St. Louis: The WU-ISCCC will build a rigorous, scientific evidence base for rapid-cycle implementation research to increase the reach, external validity, and sustainability of effective cancer control interventions. The Center’s goal and activities capture three distinct features: (1) a focus on elimination of cancer disparities; (2) the need for rapid-cycle studies; and (3) the use of systems science approaches to enhance methods and outcomes in implementation science.

NCI ISC3 Staff

April Oh
Program Director
Health Communication and Informatics Research Branch
Behavioral Research Program

Cynthia Vinson
Senior Advisor for Implementation Science

Kelly Blake
Program Director
Health Communication and Informatics Research Branch
Behavioral Research Program

Mindy Clyne
Research Assistant for Implementation Science

David Chambers
Deputy Director for Implementation Science


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