ISC3 Centers

The Implementation Science Centers in Cancer Control (ISC3) Program is a Cancer MoonshotSM initiative supporting the development, testing, and refinement of innovative approaches to implement evidence-based cancer control interventions.

All Centers feature "implementation laboratories" involving clinical and community sites. These sites engage in implementation research across the cancer control continuum to:

  • advance methods in studying implementation
  • develop and validate reliable measures of key implementation science constructs.

Research activities for the Centers are organized around a cohesive, overarching implementation science theme that frames their activities and research agenda.

Implementation Science Centers (P50s)

The ISC3 Program is composed of seven Centers funded by RFA-CA-19-005 and RFA-CA-19-006.

Implementation Science Centers (P50s)

Colorado Implementation Science Center in Cancer Control (Colorado ISC3)

Principal Investigator: Russell E. Glasgow, Ph.D.

Institution: University of Colorado School of Medicine

Theme: Advancing pragmatic implementation science approaches to assess and enhance the value of cancer prevention and control in rural primary care

Grant #: 1 P50 CA244688-01


The Implementation Science Center for Cancer Control Equity (ISCCCE)

Multiple Principal Investigators: Karen Emmons, Ph.D., Elsie Taveras, M.D., M.P.H.

Institution: Harvard T.H. Chan School of Public Health

Theme: Improving community health by integrating health equity and implementation science for evidence-based cancer control

Grant #: 1 P50 CA244433-01


Building Research in Implementation and Dissemination to close Gaps and achieve Equity in Cancer Control Center (BRIDGE-C2)

Multiple Principal Investigators: Jennifer DeVoe, M.D., D.Phil., Nathalie Huguet, Ph.D.

Institution: Oregon Health & Science University

Theme: Advancing implementation science to improve cancer screening and prevention in underserved populations

Grant #: 1 P50 CA244289-01


Penn Implementation Science Center in Cancer Control (Penn ISC3)

Multiple Principal Investigators: Rinad Beidas, Ph.D., Justin Bekelman, M.D., Robert Schnoll, Ph.D.

Institution: University of Pennsylvania/Northwestern University

Theme: Applying insights from behavioral economics to rapidly accelerate the pace at which evidence-based practices for cancer care are deployed and the extent to which they are delivered equitably, thereby increasing their reach and impact on the health and health equity of individuals with cancer

Grant #: 1 P50 CA244690-01


Optimizing Implementation in Cancer Control (OPTICC)

Multiple Principal Investigators: Bryan J. Weiner, Ph.D., Margaret Hannon, Ph.D., M.P.H., Cara C. Lewis, Ph.D.

Institution: University of Washington

Theme: Improving cancer outcomes through optimized evidence-based intervention implementation in community and clinical settings across the continuum of cancer treatment and care

Grant #: 1 P50 CA244432-01


Implementation and Informatics - Developing Adaptable Processes and Technologies for Cancer Control (iDAPT)

Multiple Principal Investigators: Kristie Long Foley, Ph.D., Thomas K. Houston II, M.D., M.P.H., Sarah L. Cutrona, M.D., M.P.H.

Institution: Wake Forest School of Medicine/University of Massachusetts Medical School

Theme: Advancing the field of implementation science by using technologies to support rapid cycle and real-time deployment and testing of implementation processes and adaptations within cancer control

Grant #: 1 P50 CA244693-01


Washington University Implementation Science Center for Cancer Control (WU-ISCCC)

Multiple Principal Investigators: Ross C. Brownson, Ph.D., Graham A. Colditz, M.D., Dr.PH.

Institution: Washington University in St. Louis

Theme: Advancing rapid-cycle implementation research to increase the reach, external validity and sustainability of effective cancer control interventions, also utilizing system science approaches to enhance methods and outcomes in implementation science

Grant #: 1 P50 CA244431-01


Last Updated
April 18, 2024