Wynne E. Norton, PhD

Wynne E. Norton
Program Director

Wynne E. Norton, Ph.D. is a Program Director in Implementation Science in the Division of Cancer Control and Population Sciences at the National Cancer Institute. Dr. Norton holds a secondary appointment in the Healthcare Delivery Research Program and serves as co-chair of the DCCPS Clinical Trials Coordination Group.

Dr. Norton’s research interests include de-implementation of ineffective interventions, evidence-based cancer care delivery, and pragmatic trials of implementation strategies. She serves as faculty for the NCI Training Institute for Dissemination and Implementation in Cancer (TIDIRC). Dr. Norton is a Program Scientist for three NCI Cancer MoonshotSM Initiatives: Accelerating Colorectal Cancer Screening and Follow-up Through Implementation Science (ACCSIS), Improving the Management of symPtoms during and following Cancer Treatment (IMPACT), and the Implementation Science Centers in Cancer Control (ISC3). She is also on the editorial board of the journal Implementation Science.

Prior to joining the NCI in 2015, Dr. Norton was an Assistant Professor at the University of Alabama at Birmingham School of Public Health. She conducted implementation research in HIV/AIDS, surgical care, cancer, and other health areas with funding from the NIH, CDC, and the Bill and Melinda Gates Foundation, among other agencies. In 2012, Dr. Norton taught a novel course in implementation science. Dr. Norton received her Ph.D. in Social Psychology from the University of Connecticut (2009). Her dissertation was funded by an individual National Research Service Award from the National Institute of Mental Health. Dr. Norton received her B.A. in Psychology with honors from the College of William and Mary (2004).

Select Publications

  • Norton WE, Loudon K, Chambers DA, Zwarenstein M. Designing provider-focused implementation trials with purpose and intent: Introducing the PRECIS-2-PS tool. Implement Sci. 2021;16(1):7. doi: 1186/s13012-020-01075-y
  • Norton WE, Chambers DA. Unpacking the complexities of de-implementing inappropriate health interventions. Implement Sci. 2020;15(1):2. doi: 1186/s13012-019-0960-9.
  • Norton WE, Chambers DA, Kramer BS. Conceptualizing de-implementation in cancer care delivery. J Clin Oncol. 2019;37(2):93-96. doi:1200/JCO.18.00589.
  • Norton WE, McCaskill-Stevens W, Chambers DA, Stella PJ, Brawley OW, Kramer BS. De-implementing ineffective and low-value clinical practices: Research and practice opportunities in community oncology settings. JNCI Cancer Spectr. 2021;5(2). doi: 1093/jncics/pkab020
  • Chambers DA, Vinson CA, Norton WEAdvancing the Science of Implementation Across the Cancer Continuum. New York, NY: Oxford University Press; 2018.
  • Chambers DA, Norton WE. The adaptome: advancing the science of intervention adaptation. Am J Prev Med. 2016;51(4 Suppl 2):S124-31. doi: 1016/j.amepre.2016.05.011


  • Implementation of evidence-based practices in cancer care delivery
  • De-implementation of ineffective practices across the cancer control continuum
  • Pragmatic trials in implementation science
Last Updated
December 09, 2021