Event Series
Obesity and Cancer
Obesity is associated with and likely plays a causal role in at least thirteen types of cancer. Worsening obesity tends to increase serum concentrations of glucose, insulin, insulin-like growth factor-1 (IGF-1), lipids, leptin, estrogen, resistin, and inflammatory cytokines and reduces IGF-binding protein and adiponectin levels, each of which has been suggested to contribute to cancer pathogenesis. In this forum, we focused on evidence regarding a potential mechanistic link between obesity-driven inflammation and tumor development.
This webinar is part of the NCI Obesity & Cancer Webinar Series, which aims to foster cross-disciplinary research on obesity that can help prevent, treat, and/or control cancer.
Speakers
Obesity-associated inflammation drives estrogen signaling in breast cancer
Associate Attending,
Breast Medicine Service,
Memorial Sloan Kettering Cancer Center
Inflammation modulation by adipocytes and the adipose tissue microenvironment
Director, Diabetes and Metabolism Research Center,
Professor of Internal Medicine,
Division of Endocrinology, Diabetes, and Metabolism,
The Ohio State University
Inflammation and ceramides in colorectal cancer
Chief Scientific Officer and Executive Director of the Comprehensive Cancer Center, Huntsman Cancer Institute,
Jon M. and Karen Huntsman Presidential Professor in Cancer Research,
University of Utah
Inflammation and ceramides in colorectal cancer
Co-Director, Diabetes & Metabolism Research Center,
Department Chair, Nutrition & Integrative Physiology,
Professor, Nutrition & Integrative Physiology,
Distinguished Professor, Nutrition & Integrative Physiology,
University of Utah
Moderator
Program Director,
NCI Division of Cancer Biology