Tobacco Regulatory Science

The Tobacco Regulatory Science Program (TRSP) is an interagency partnership between the NIH and the Food and Drug Administration (FDA) Center for Tobacco Products.

About the Tobacco Regulatory Science Program

With the passage of the Family Smoking Prevention and Tobacco Control Act (often called the Tobacco Control Act) in 2009, the FDA acquired the authority to regulate the manufacture, marketing, and distribution of tobacco products in order to protect public health and established a new Center for Tobacco Products (CTP). Within the framework of the Tobacco Control Act, the NIH and FDA/CTP formed an interagency partnership to foster research that informs FDA/CTP tobacco regulatory activities. This partnership leverages the NIH’s infrastructure to solicit, review, and manage research, the long-standing support for tobacco-related research at several NIH Institutes and Centers, and the FDA’s expertise and authority in tobacco regulatory science. The National Cancer Institute is a participating Institute in the Tobacco Regulatory Science Program and holds a diverse portfolio of tobacco regulatory science grants.

Funded Research

Tobacco Centers of Regulatory Science (TCORS)

The Tobacco Centers of Regulatory Science (TCORS) generate critical research to inform the FDA’s regulation of tobacco products. The TCORS are made up of investigators with a broad range of expertise (including epidemiology, economics, toxicology, addictions, and marketing) who conduct research projects around an integrative theme. In 2013, 14 Centers (TCORS 1.0) were funded, and in 2018, nine Centers (TCORS 2.0) received funding. NCI programmatically manages four of the nine TCORS 2.0 Centers.

Featured Grantees

Other Funded Research

View a list of NCI grants funded through TRSP in current and prior fiscal years.

View all tobacco regulatory research grants across NIH Institutes that have participated in TRSP in current and prior fiscal years.

Funding Opportunities

Title Announcement # Expiration Date Resources
Tobacco Regulatory Science (R01 Clinical Trial Optional) RFA-OD-21-002 February 15, 2023
Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed) RFA-OD-21-004 March 9, 2023
Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed) RFA-OD-21-003 March 9, 2023


Resources for Interested Applicants

Selected Tobacco Regulatory Science Research and Reports

Last Updated
November 10, 2022