Reviews literature on genetic studies of nicotine use and dependence and presents a scientific plan for incorporating genetic research into cross-disciplinary studies of nicotine dependence. Chapters highlight theoretical considerations (including linking heritable genetic traits with nicotine dependence), modeling developmental trajectories to dependence, candidate endophenotypes, epidemiological and methodological considerations, and future directions.
The tobacco monographs can be ordered by sending an email to firstname.lastname@example.org. Please include the title and/or NCI Publication Number and the requested quantity.*
* Both Executive Summary (Publication ID: T141) and full reports (Publication ID: T140) available.
National Cancer Institute. Phenotypes and Endophenotypes: Foundations for Genetic Studies of Nicotine Use and Dependence. Tobacco Control Monograph No. 20. Bethesda, MD: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute. NIH Publication No. 09-6366, August 2009.
View Individual Chapters
Chapters and key topics covered within each chapter are listed below. Chapters generally include an introductory section, details on methodology, a chapter summary, research needs, and a reference list.