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National Cancer Institute

Obesity Prevention and Energy Balance

The term, "energy balance" as applied to human health, typically refers to the integrated effects of diet, physical activity, and genetics on growth and body weight over an individual’s lifetime. Increasingly, evidence supports the importance of understanding the effects of energy balance on cancer prevention, development, and progression and on cancer survivors’ quality of life. Weight, body composition, physical activity, and diet affect numerous physiological systems and can influence the cancer process at many points. The Health Behaviors Research Branch supports research that explores the effect of energy balance (obesity and overweight) on cancer prevention and relevant approaches with broad population impact.


Linda Nebeling, Ph.D., M.P.H., R.D.

Frank M. Perna, Ed.D., Ph.D.

Tanya Agurs-Collins, Ph.D., R.D.

View all Health Promotion Funding Opportunities


National Collaborative on Childhood Obesity Research – (NCCOR) exit disclaimer

The National Collaborative on Childhood Obesity Research (NCCOR) brings together four of the nation’s leading research funders – the Centers for Disease Prevention and Control (CDC), the National Institutes of Health (NIH), the U.S. Department of Agriculture (USDA) and the Robert Wood Johnson Foundation (RWJF) – to improve the efficiency, effectiveness and application of childhood obesity research and to produce positive changes more rapidly through enhanced coordination and collaboration.

Transdisciplinary Research on Energetics and Cancer (TREC)exit disclaimer

Transdisciplinary Research on Energetics and Cancer (TREC) initiative fosters collaboration among transdisciplinary teams of scientists with the goal of accelerating progress toward reducing cancer incidence, morbidity, and mortality associated with obesity, low levels of physical activity, and poor diet. It also will provide training opportunities for new and established scientists to carry out integrative research on energetics and energy balance. The TREC initiative complements NCI’s other energy balance research endeavors and efforts of the NIH Obesity Task Force.


Information on NIH Obesity Research