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National Cancer Institute

Transdisciplinary Research on Energetics and Cancer (TREC) Centers

TREC - Transdisciplinary Research on Energetics and Cancer Centers

Transdisciplinary Research on Energetics and Cancer (TREC) Centers Exit Disclaimer
The Transdisciplinary Research on Energetics and Cancer Centers initiative fosters collaboration across multiple disciplines and encompasses projects that cover the biology, genomics, and genetics of energy balance to behavioral, sociocultural, and environmental influences upon nutrition, physical activity, weight, energetics, and cancer risk. It provides training opportunities for new and established scientists who can carry out integrative research on energetics and energy balance. The TREC initiative complements NCI’s energy balance research endeavors and efforts of the NIH Obesity Task Force.

The 2011–2016 Transdisciplinary Research on Energetics and Cancer (TREC) Initiative: Rationale and Design. Ruth E. Patterson, Graham A. Colditz, Frank B. Hu, Kathryn H. Schmitz, et al,. Cancer Causes Control (2013) 24:695–704.

2011 – 2016 NCI-funded TREC Research Centers

TREC Research Center Principal Investigator
University of California – San Diego Exit Disclaimer
San Diego, CA
Dr. Ruth Patterson
The TREC Research Center at the University of California, San Diego focuses on mechanisms linking obesity with breast cancer risk and conducts studies investigating obesity and lifestyle factors related to insulin resistance and inflammation using mouse models, clinical trials, and wireless and networked technologies in the community.
University of Pennsylvania
Philadelphia, PA
Dr. Kathryn Schmitz
The University of Pennsylvania TREC Research Center focuses on the association between energy balance and breast cancer recurrence and persistent adverse treatments effects and explores the impact of exercise and weight control interventions in cancer survivors through cost effectiveness analysis.
Harvard Exit Disclaimer
Boston, MA
Dr. Frank Hu
The Harvard TREC Research Center focuses on biological mechanisms linking obesity and cancer throughout the lifespan and at multiple levels, and translating this knowledge into actionable behavioral interventions targeting children, minorities, and cancer survivors.
Washington University in St. Louis Exit Disclaimer
St. Louis, MO
Dr. Graham Colditz
The TREC Research Center at Washington University in St. Louis uses multilevel and multigenerational approaches to investigate mechanisms by which preconception diet, nutrition and built environment policies impact inactivity and how physical activity and energy balance influence body weight and carcinogenesis across the lifespan.
Coordination Center - Fred Hutchinson Cancer Research Center
Seattle, WA
Dr. Mark Thornquist
The TREC Coordination Center at Fred Hutchinson Cancer Research Center integrates efforts across the network of individual TREC Research Centers and facilitates transdisciplinary research by supporting communication, scientific collaboration, logistical infrastructure for data management and bioinformatics, results dissemination, training, and evaluation.

NCI Contact
Dr. Linda Nebeling
linda.nebeling@nih.gov

Dr. Tanya Agurs-Collins
collinsta@mail.nih.gov

View the TREC publications database Exit Disclaimer

View the TREC Connect e-newsletter archives

TREC Initiative Midcourse Update (PDF), March 2009

2005 – 2010 NCI-funded TREC Research Centers

TREC Research Center Principal Investigator
The University of Minnesota
Minneapolis, MN
Dr. Robert Jeffery
Fred Hutchinson Cancer Research Center
Seattle, WA
Dr. Anne McTiernan
University of Southern California
Los Angeles, CA
Dr. Michael Goran
Case Western Reserve University
Cleveland, OH
Dr. Nathan Berger
Coordination Center - Fred Hutchinson Cancer Research Center
Seattle, WA
Dr. Mark Thornquist