Stress and Aging in Hematopoietic Stem Cell Transplantation and Cellular Therapy

This presentation will provide a conceptual framework outlining the biological aging mechanisms through which stress and adversity impact clinical outcomes in hematopoietic stem cell transplantation and cellular therapy (TCT). Dr. Jennifer Knight will discuss the implications of socioenvironmental stress on biological and immunological signaling patterns and their impact on clinical outcomes among TCT recipients. Dr. Kelly Rentscher will then review research on stress-induced biological aging and present new findings linking chronic stress, biological aging, and clinical and functional (i.e., cognitive and physical function) outcomes in TCT recipients. Presenters will conclude with a discussion of actionable strategies to target these biological mechanisms to improve equity, treatment response, and survivorship for TCT recipients. 

This webinar is part of the Perspectives on Cancer and Aging: The Arti Hurria Memorial Webinar Series. It is co-hosted by the NCI Behavioral Research Program and Epidemiology and Genomics Research Program.

Reasonable Accommodations
Closed captioning will be available to all participants. Individuals who need reasonable accommodations to participate in this event should contact ncidccpsbrpadvances@mail.nih.gov. Requests should be made at least five business days in advance of the event.